Then I think I'm good with a personal ultimate for now. S3Drive also works to copy/sync an on-device Android Seedvault backup (on GrapheneOS) to S3 storage, without breaking the backup creation process, like it happens occasionally when you write directly to Koofr webdav, for example. Android write for the S3 mount potentially would make this even easier in the future.
For business use cases, user administration and management/deployment of secrets and such would likely be what admins need to provision S3Drive. StorJ is working on some file stream or fuse mount products, but focused on large media stuff only, afaik. Trying to keep the local user end point/client free from (corporate) files/content is a common goal that could be accomplished with S3Drive. This is where Google Drive file stream app is so convenient, and without much real competition aside from Insync on Linux. And no one does this reliably with open source e2e encryption yet.